Today’s Sleep Headlines …
Event-Weighted Desaturation Burden and Cardiovascular Mortality in Sleep Apnoea: Findings from a Large Community-Based Prospective Cohort
CONCLUSIONS: EWDB was independently associated with cardiovascular mortality and provided incremental prognostic information beyond established clinical and sleep-related factors in this cohort. By integrating respiratory event intensity, cumulative burden, and inter-event interval regularity, EWDB may…
Read full source →Shift work and hormonal-circadian disruption raise urinary incontinence: a narrative review
CONCLUSIONS: Management of UI should move beyond a purely mechanical perspective toward an integrated model encompassing hormonal, metabolic, and behavioral modulation. Understanding the interactions among circadian rhythms, endocrine control, and pelvic tissue physiology may open…
Read full source →Energy drinks consumption and sleeping quality of students' universities of the Chiclayo province, Peru
CONCLUSIONS: The study confirms a strong negative relationship between energy drink consumption and sleep quality among university students in Chiclayo. These findings highlight that stimulant intake constitutes a significant risk factor that undermines restorative sleep,…
Read full source →Protective role of high-intensity exercise and lactate against sleep deprivation-induced alterations in hippocampal gene expression and spatial learning
Sleep deprivation impairs cognitive function by disrupting hippocampal signaling pathways essential for memory formation. High-intensity interval training (HIIT) and lactate, a metabolic byproduct of exercise, have demonstrated potential benefits for brain plasticity, but their protective…
Read full source →Multidimensional sleep characteristics and arterial stiffness in older adults
CONCLUSIONS: In older adults, poorer sleep restfulness and nocturia were associated with arterial stiffness, although these associations warrant cautious interpretation as an exploratory finding. CAVI also differed according to TIB category. These findings may provide…
Read full source →Managing Dissociation and Somatic Symptoms in Complex PTSD Using a Structural Dissociation-informed Approach: A Case Report
Chronic interpersonal trauma can lead to complex clinical presentations characterized by dissociation, somatic symptoms, and disturbances in self-organization, particularly when psychosocial stressors remain active. This case report describes a 32-year-old female with prolonged interpersonal trauma…
Read full source →Effect of a Single Subanesthetic Dose of Esketamine on Gastrointestinal Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized, Outcome-Assessor-Blinded, Placebo-Controlled Trial
CONCLUSION: Intraoperative esketamine accelerates gastrointestinal function recovery after laparoscopic colorectal surgery, especially reducing postoperative gastrointestinal intolerance symptoms of nausea and distension while improving early sleep quality. However, no evident benefit was observed in reducing hospital…
Read full source →Bifidobacterium adolescentis SBT2786-induced early-night sleep requires CCHamide-1 signaling in Drosophila ellipsoid body ring neuron circuits
We previously identified the sleep-promoting bacterium Bifidobacterium adolescentis SBT2786; however, its molecular mechanism remains unknown. In Drosophila melanogaster, tissue-/region-specific RNA interference (RNAi) targeted the gut-brain neuropeptide CCHamide-1 (CCHa1) and the CCHa1 receptor (CCHa1R). The increase…
Read full source →From Mechanistic Evidence to Clinical Translation: A Narrative Review of Chinese Herbal Medicine for Insomnia
Insomnia is one of the most common sleep disorders and a major public health problem worldwide. Chinese herbal medicine (CHM) is widely used as a complementary and alternative approach for chronic insomnia. Clinical studies have…
Read full source →Developing a Theory-Based Sleep Hygiene Education Intervention for Adults with Insomnia: An Intervention Mapping and Content Validation Study
CONCLUSION: This study presents a structured development and content validation of a theory-driven SHE program informed by behavioral science, empirical evidence, and stakeholder input. The intervention targets key limitations of traditional SHE approaches and provides…
Read full source →Sleep trajectories in pregnancy: associations with trauma exposure, PTSD, and postpartum depression
Sleep during the perinatal period is often highly disrupted due to maternal biopsychosocial changes that accompany pregnancy. Poor sleep quality is a symptom of PTSD, while insomnia often emerges after a traumatic event and commonly…
Read full source →Effects of Orexin Receptor Antagonists on Nocturia and Overactive Bladder Symptoms in Patients with Insomnia: A Single-Center Retrospective Study
CONCLUSIONS: ORA treatment was found to be effective and safe in insomnia patients with nocturia. The findings suggest that ORAs may improve nocturia and OAB symptoms in patients with insomnia.
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