Pantoprazole and Other Proton Pump Inhibitors, Sleep, and Cardiovascular Safety: A Research Breakdown

This is an editorial, not an original study. The authors set out to weigh the evidence for and against a link between proton pump inhibitors (PPIs) and cardiovascular disease. They also raise a pathway that gets little attention in this debate. PPIs affect sleep, and poor sleep is tied to hypertension, metabolic problems, and cardiovascular… Continue reading

Cognitive Behavior vs Bright Light Therapy for Insomnia in Women Undergoing Chemotherapy for Breast Cancer: A Randomized Clinical Trial

The SleepCARE trial tested whether cognitive behavior therapy for insomnia (CBT-I) and bright light therapy (BLT) reduce insomnia and fatigue symptoms in women having chemotherapy for breast cancer. It also tested whether combining the two works better than either alone. No prior RCT had compared CBT-I and BLT head to head, or tested them together,… Continue reading

In adults, does untreated obstructive sleep apnea, compared with no OSA, increase the risk of atrial fibrillation?

Clnical answer: Yes. Untreated OSA is an independent risk factor for AF, and the evidence base is now stronger and more mechanistic than a simple association. The American Heart Association states OSA is an independent AF risk factor even without other cardiac disease, though a fully proven causal pathway is still being established. Source of… Continue reading

In adults sleeping with a bed partner, does partner snoring versus a non-snoring partner disrupt the non-snoring partner’s sleep quality?

Clinical Answer: Yes. A snoring bed partner disrupts sleep more than a non-snoring partner, based on consistent findings across polysomnography and subjective sleep reports. Source Of Recommendation: B (inconsistent or limited-quality patient-oriented evidence). Evidence used: Objective polysomnography from a small crossover study of 10 couples found that eliminating snoring with CPAP cut the partner’s arousal… Continue reading

In adolescents who use digital screens in the evening, does wearing blue light blocking glasses, compared to not wearing them, reduce insomnia symptoms or improve sleep?

Clincial Answer: The evidence does not support blue light blocking glasses alone as an effective treatment to prevent or reduce insomnia in adolescents. Small trials show the glasses blunt screen induced melatonin suppression and can modestly advance sleep timing, and the one larger, well conducted 2026 trial that showed a real gain in sleep duration… Continue reading